Installation

Download EDuke32 Wii.
Extract the archive to the root of your SD card.
Place the DUKE3D.GRP and DUKE.RTS game data files in sd:/apps/eduke32/ (if you are using an SD card, for example). If you are unsure where to find these files, see the EDukeWiki Installation and configuration page.
To hear the MIDI music, install a soundfont to be used by the included Timidity software.
As an example, try using Freepats, a recommended soundfont. You can install Freepats by the following method:
Download freepats-20060219.zip.
Extract the contents of freepats-20060219.zip directly to "sd:/usr/local/lib/timidity/".
Copy freepats.cfg from that directory to "sd:/etc/timidity/". The file crude.cfg can also be used if you encounter problems with EDuke32 Wii running low on memory.
Rename the cfg file you just copied to be named timidity.cfg.
Launch the game using your loader.